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Vacuum freeze-drying technology (often simply referred to as freeze-drying technology) is a comprehensive interdisciplinary technology. Its research object is the heat transfer and mass transfer processes of frozen materials in a vacuum environment, as well as the characteristics and laws of these processes. The development of this technology cannot be separated from the support of related technologies such as vacuum refrigeration, heating, mechanical transmission, and automatic control.
The principle of vacuum freeze-drying is based on the three-phase diagram of water. When the pressure is below the triple point pressure of water (that is, 610.5 pascals), liquid water does not exist. Solid ice can directly sublime into water vapor. During this process, as long as an appropriate amount of heat is provided, the ice will absorb heat and sublime into gas, thereby achieving the dehydration of the material. Therefore, it is also called freeze sublimation drying.